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Binding of hypoglycaemic sulphonylureas to an artificial phospholipid bilayer

机译：低血糖磺酰脲与人工磷脂双层的结合

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Hypoglycaemic sulphonylureas bind to multilamellar liposomes formed of egg yolk phosphatidylcholine. In this artificial model, both specific and non-specific components of the binding phenomenon can be characterized by the same criteria as those used in studies performed with natural membranes. The relative ability of distinct sulphonylureas to inhibit the binding of 3H-glibenclamide or 3H-gliquidone to the liposomes parallels their relative potency as insulin secretagogues. It is proposed that the insertion of hypoglycaemic sulphonylureas into the phospholipid domain of the B cell membrane could represent a primary event in the mechanism by which these agents stimulate insulin release. © 1984 Springer-Verlag.

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作者
Deleers, Michel; Malaisse, Willy;
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年度 1984
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专利

1. Binding of tritiated S21403 to an artificial phospholipid bilayer. [J] . Malaisse WJ, Dard Brunelle-B Research communications in molecular pathology and pharmacology . 1999,第3期

机译：ti化的S21403与人工磷脂双层的结合。
2. Interactions of small molecules with phospholipid bilayers. Binding to egg phosphatidylcholine of some organic anions (bromosulphophthalein, oestrone sulphate, haem and bilirubin) that bind to ligandin and aminoazo-dye-binding protein A [J] . B Ketterer, E Tipping, L Christodoulides The biochemical journal . 1979,第2期

机译：小分子与磷脂双层的相互作用。与卵磷脂结合的一些有机阴离子（溴代酞菁，硫酸雌酮，血红素和胆红素）与配体蛋白和氨基偶氮染料结合蛋白A结合
3. Interactions of small molecules with phospholipid bilayers. Binding to egg phosphatidylcholine of some uncharged molecules (2-acetylaminofluorene, 4-dimethylaminoazobenzene, oestrone and testosterone) that bind to ligandin and aminoazo-dye-binding protein A [J] . Brian Ketterer, Edward Tipping, Lucia Christodoulides The biochemical journal . 1979,第2期

机译：小分子与磷脂双层的相互作用。与卵磷脂结合的一些不带电荷分子（2-乙酰氨基芴，4-二甲基氨基偶氮苯，雌酮和睾丸激素）与配体蛋白和氨基偶氮染料结合蛋白A结合
4. Dynamic Photonic Crystals Mainly Composed of Water: Sensitive Changes of Structural Colors Exhibited by Thermoresponsive Phospholipid Bilayers [C] . Noriyuki Uchida, Zhi Wei Kenny Low, Yasuhiro Ishida 日本化学会春季年会講演予稿集 . 2018

机译：动态光子晶体主要由水组成：热敏磷脂双层呈现的结构颜色的敏感变化
5. Chapter 1: (I) Use of chain-modified phospholipids to determine water content of bilayers. (II) Ion transport across bilayers of chain-modified phospholipids. Chapter 2: Synthesis, catalytic properties of and studies toward electron transport by copper-complexed lipids. [D] . Aikens, Patricia Ann Elizabeth. 1990

机译：第1章：（I）使用链修饰的磷脂测定双层的水含量。（II）跨链修饰的磷脂的双层的离子运输。第2章：铜络合物脂质的合成，催化性能以及对电子的研究。
6. Tetracycline diffusion through phospholipid bilayers and binding to phospholipids. [O] . M Argast, C F Beck 1984

机译：四环素通过磷脂双层扩散并与磷脂结合。
7. Tetracycline diffusion through phospholipid bilayers and binding to phospholipids. [O] . Argast, M, Beck, C F 1984

机译：四环素通过磷脂双层扩散并与磷脂结合。

Binding of hypoglycaemic sulphonylureas to an artificial phospholipid bilayer

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